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[simpli.com](https://www.simpli.com/history/understanding-different-types-lawyers-comprehensive-overview?ad=dirN&qo=serpIndex&o=740008&origq=lawyers+in+my+area)These tails are subject to several post-translational covalent modifications, together with acetylation, phosphorylation, ubiquitination, sumoylation and methylation (reviewed in 1 ). Methylation been found on a spread of lysine residues in various histones: K4 (using the one-letter amino-acid code for lysine), K9, K27, K36 and K79 in histone H3, K20 in histone H4, K59 within the globular domain of histone H4 2 and K26 of histone H1B three Several proteins liable for the methylation of specific residues have been characterised, and all but one of these incorporates a SET area |