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If you loved this article so you would like to obtain more info with regards to lawyer in my area kindly visit our web page. As an example, human SET7/9 has recently been reported to methylate Lys189 within the common transcription issue TAF10, resulting in an increased affinity for RNA polymerase II and transcriptional activation of sure TAF10-dependent genes 37 SET7/9 has also been reported to methylate p53, increasing the steadiness of this brief lived tumor-suppressor protein 38 These observations counsel that we should not narrowly define the SET-domain proteins as histone lysine methyltransferases but instead call them protein lysine methyltransferases.

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