We found that acute lysine ingestion at average doses (i.e., 2 or 5 g) has no favorable affect on endogenous glucose Ra, endogenous glucose Rd, glucose AUC, insulin AUC or ISI/M in older, overweight individuals.
[reference.com](https://www.reference.com/world-view/article-48-2790ef24047266f4?ad=dirN&qo=paaIndex&o=740005&origq=solicitor+article)I do know that I have not had a chilly sore since taking these.